Redefining the Cold Chain: How Liquid Cooling Can Pay Off with Air-Cycle Invention by Mirai Intex

Mirai Intex has become an icon of disruptive companies in the race towards decarbonization of the cooling sector. As global industries demand more environmentally friendly and cost-effective thermal management, the air-cycle technology patented by the company comes as a unique solution, with zero usage of all synthetic gases.

Companies across the globe are using Mirai Intex to find out the benefits of liquid cooling in cryotherapy research, data center management, and many more. In case you want to introduce environmentally friendly, high-quality solutions, please do not hesitate to contact us and request consultancy and custom-built systems.

Global Climate Imperative: Cooling without Compromise

Almost 10 percent of all carbon dioxide emissions in the world are produced by cooling systems, which is an overwhelming statistic that is only likely to increase to 20 percent by the year 2050 unless solutions to the problem are applied. The traditional systems operate using hydrofluorocarbons (HFCs), and these have a high global warming potential thousands of times greater than CO₂. 

Moreover, Mirai Intex cooling units have natural ambient air (R729) as a refrigerant, thus avoiding these environmentally hazardous synthetic gases altogether.

This is not only a compliance matter. It is a matter of duty and chance. The delisting of HFCs is already part of the global standards, such as the Kigali Amendment or the European F-Gas regulations, so Mirai Intex is not only at the forefront of the change, but it has been driving it.

How The Technology Works: The Air-Cycle Cooling Power

The current features of the Mirai Intex product line lie in the turbo-compression-expansion machine, which is a high-speed, oil-free air-cycle machine that enables ultra-low temperatures without direct emission of greenhouse gases. The Mirai machines compress air, then cool it via recuperative heat exchange and expand it to provide refrigeration, unlike the vapor-compression systems.

The result? High effective cooling and high constant low performance of cooling to -130°C without man-made refrigerants, without oil, and no defrosting.

Mirai has two versions of the air cycle:

• Open-Cycle Units: Such chillers force fresh air into chambers/enclosures after placing them and compressing and cooling them. It is suitable in cold rooms and blast freezers.
• Closed-Cycle Units: Secondary fluids (ethanol, glycol, silicone oils) are used to carry cold through a closed recirculating loop and provide a very controlled environment and safeguard sensitive products.

Why Liquid Cooling Is a Game Changer

So where does liquid cooling come in—and why does it matter?

Liquid cooling is the process of transferring heat away using a fluid medium rather than air. While air cooling remains common, liquid cooling is exponentially more efficient and stable. When paired with Mirai Intex’s air-cycle chillers, this method creates a hybrid system capable of:

• Faster heat removal
• Finer temperature regulation
• Reduced noise
• Smaller equipment footprints
• Longer lifespan and lower maintenance
  

This makes it perfect for temperature-sensitive applications—such as biotech labs, semiconductor manufacturing, and medical cold storage—where mere degrees can make the difference between success and failure.

Real Benefits of Liquid Cooling by Mirai Intex

So, what are the main advantages of liquid cooling operating on the air-cycle technology used by Mirai?

1. Occupying Ozone Safety Subordinate and environmental Responsibility

• Zero Global Warming Potential (GWP)
• Zero Ozone Depletion Potential (ODP)
• Adherence to EU and international laws Full adherence to EU and international laws

2. Ultra-Low Temperature Range

• In a closed cycle, the temperature can go down to -160 degrees Celsius.
• It is very suitable in applications such as cryoprotection, freeze-drying, and the storage of vaccines

3. FILTER Maintenance—Light Operation Oil-Free

• The harm to the bearings is minor, and the oils are not necessary since the bearing is magnetic
• Long-run components (90,000+ hours lifetime)

4. Energy recovery systems

Recuperative exchangers recycle cold energy, increasing the overall efficiency by 20-30%.

5. Does not require Defrosting

The inventor holds a US patent on a contraption called the snow catcher that pre-compresses humidity to avoid an ice build-up and energy.

Real-World Applications

Mirai Intex’s systems are already making measurable impacts across industries:

1. Cryotherapy and Medical Cooling

Mirai’s MIRAI X CRYO unit delivers ultra-low, stable temperatures for cryochambers used in sports medicine, physical therapy, and mental health treatment—without relying on nitrogen or freon-based gases.

2. Pharmaceutical & Biotech Labs

For vaccine preservation, plasma storage, and genetic research, even a 0.5°C fluctuation can spell disaster. Mirai’s closed-cycle chillers ensure reliable, oil-free precision.

3. Data Centers and Electronics

With servers pushing the limits of performance and generating massive heat, liquid cooling systems powered by Mirai Intex offer scalable, silent, and space-efficient cooling.

4. Industrial Freeze-Drying

Mirai’s technology integrates seamlessly with industrial freeze-dryers, replacing liquid nitrogen or CO₂ with air-cycle cooling for better efficiency and drastically reduced emissions.

Innovation Recognized Globally

Mirai Intex’s achievements haven’t gone unnoticed. The company won the 2024 RAC Cooling Industry Award for Refrigeration Innovation of the Year for its MIRAI X CRYO system. It also earned the ATMO Natural Refrigerants Label, a global certification for clean cooling solutions.

Additionally, its collaboration with top-tier companies such as GEA, HOF Sonderanlagenbau, and Pfizer contractors has resulted in high-performance cryogenic solutions that eliminate hazardous refrigerants while outperforming conventional systems.

Intelligent Functionality & Digitalisation

Mirai Intex would not be satisfied with cooling the systems; it is developing more intelligent systems.

• Smart Control Interfaces: Remote monitoring and diagnostics on stores with touchscreen panels.
• Variable Capacity Regulation: Flexible range of loads (3-100 percent) energy-efficient.
• Plug-and-Play Modularity: Expanded systems in the future.

These qualities do not only contribute to the high performance of the units but also their readiness towards the future, including the ability to be included in smart buildings, platforms, and cloud categories.

Forecasted Future and World Presence

With its headquarters in the Czech Republic, Mirai Intex markets itself to the world with distribution in Europe and Asia as well as North America. This is seen in aerospace and advanced medicine, where the company has continued to develop its products to suit the stringent industries.

Future innovations are:

• MIRAI Cold 150 T—A new closed-cycle chiller that is more portable, even against the outdoors MIRAI Cold 100 T—A reinforced portability retained chiller (outdoor use)
• MIRAI X CRYO 40—a cryochiller with a large cryo-capacity and high performance
• An Artificial intelligence (AI)-based diagnostics and predictive maintenance tools

Final Thoughts

The global cooling crisis needs something more than the small and gradual steps that will help improve it, but something radical that will help make big and significant improvements. Exactly that, which is available to you right now at Mirai Intex: a proven, zero-emission, oil-free technology, which is already creating new standards.

By taking advantage of the benefits of liquid cooling, you are increasing the performance and efficiency but also making the world a safer place. Both in case you are interested in retrofitting your current systems, and in case you want to design a future-proof system on a blank sheet, Mirai Intex can assist you.

Call us now regarding how the future of cooling can be quiet, clean, cold, and 100 percent compliant.